Intracept® for Low Back Pain


Chron­ic low back pain can dis­rupt your dai­ly life and take a toll on both your phys­i­cal and men­tal well-being. Fac­tors like a seden­tary lifestyle, genet­ics, and aging make this con­di­tion all too com­mon — affect­ing near­ly 30% of U.S. adults in 2018 alone.

At The South Bend Clin­ic, we offer the Intra­cept® pro­ce­dure, a min­i­mal­ly inva­sive, long-last­ing solu­tion for ver­te­bro­genic pain. By tar­get­ing the root cause, Intra­cept® helps patients find real relief and regain mobility.

What is Ver­te­bro­genic Pain? 

Ver­te­bro­genic pain is a dis­tinct type of chron­ic low back pain caused by dam­age to ver­te­bral end­plates, the tis­sue that cov­ers the top and the bot­tom of each ver­te­bral body and sep­a­rates it from the disc. Disc degen­er­a­tion, and the wear and tear that occurs with every­day liv­ing, pro­duces stress­es on the end­plates that dam­age them, lead­ing to inflam­ma­tion and ver­te­bro­genic pain. The basiver­te­bral nerve (BVN), found with­in the ver­te­brae, car­ries pain sig­nals from the inflamed end­plates to the brain. 

How Do Patients Describe Ver­te­bro­genic Pain? 

The disc and end­plate are both part of the ante­ri­or spinal col­umn and pro­duce sim­i­lar low back pain symp­toms. How­ev­er, end­plate pain is asso­ci­at­ed with dis­tinc­tive changes on rou­tine MRI called Mod­ic changes. Patients who find relief from the Intra­cept Pro­ce­dure often describe pain in the mid­dle of their low back that is made worse by phys­i­cal activ­i­ty, pro­longed sit­ting, and bend­ing for­ward or with bend­ing and lift­ing. ¹

The basiver­te­bral nerve (BVN) enters the bone at the back of the ver­te­bral body (the bones in your spine) and branch­es” to the end­plates (that are locat­ed at the top and the bot­tom of each ver­te­bral body). When end­plates are dam­aged, these nerve end­ings increase in num­ber and pick up” pain sig­nals that are then sent to the brain through the BVN. The Intra­cept® Pro­ce­dure relieves ver­te­bro­genic pain by heat­ing the basiver­te­bral nerve (BVN) with a radiofre­quen­cy probe to stop it from send­ing pain sig­nals to the brain. 

How does the Intra­cept® Pro­ce­dure Work? 

The Intra­cept Pro­ce­dure is a min­i­mal­ly inva­sive, implant free pro­ce­dure that pre­serves the over­all struc­ture of the spine. The Intra­cept Pro­ce­dure is a same-day, out­pa­tient pro­ce­dure. Patients are under anes­the­sia, and the pro­ce­dure gen­er­al­ly lasts an hour. The pro­ce­dure is FDA-cleared and is proven in mul­ti­ple stud­ies to be safe, effec­tive, and durable. ²’³


How Long Does Pain Relief Last fol­low­ing the Intra­cept® Procedure? 

Clin­i­cal evi­dence demon­strates the major­i­ty of patients expe­ri­ence sig­nif­i­cant improve­ments in func­tion and pain 3‑months post pro­ce­dure that are sus­tained more than 5 years after a sin­gle treat­ment. ²

How Do I Know If I’m a Can­di­date for Intracept®? 

Patients who have expe­ri­enced chron­ic low back pain for at least six months, have tried con­ser­v­a­tive treat­ments with­out suc­cess, and have MRI find­ings show­ing Mod­ic changes — which indi­cate ver­te­bral end­plate dam­age and inflam­ma­tion — may be can­di­dates for the Intra­cept® Pro­ce­dure. As with any med­ical pro­ce­dure, poten­tial risks should be care­ful­ly dis­cussed with a health­care provider to deter­mine if Intra­cept® is the right solu­tion for long-term pain relief.

Koreck­ij T, Krein­er S, Khalil JG, Smuck M, Mark­man J, Garfin S. Prospec­tive, ran­dom­ized, mul­ti­cen­ter study of intraosseous basiver­te­bral nerve abla­tion for the treat­ment of chron­ic low back pain: 24-month treat­ment arm results. NASSJ. Pub­lished online Octo­ber 26, 2021. DOI: https://​doi​.org/​1​0​.​1​0​1​6​/​j​.xnsj….
2 Fis­chgrund J, Rhyne A, Macadaeg K, et al. Long-term out­comes fol­low­ing intraosseous basiver­te­bral nerve abla­tion for the treat­ment of chron­ic low back pain: 5‑year treat­ment arm results from a prospec­tive ran­dom­ized dou­ble-blind sham-con­trolled mul­ti-cen­ter study. Eur Spine J. 2020;29(8):1925 – 34. doi​.org/​1​0​.​1​0​0​7​/​s​0​0​5​8​6-020 – 06448‑x
3 Relievant data on file as of Jan­u­ary 2023.